Polyposis coli and colon carcinoma

Familial polyposis (FAP) is an autosomal dominant
hereditary disease. In late childhood and
early adulthood, up to 1000 and more polyps
develop in the mucous membrane of the large
intestine (colon) (1). Each polyp can develop
into a carcinoma (2). In about 85% of affected
persons, small hypertrophic areas that do not
affect vision are present in the retina (3).
Hereditary non-polyposis colorectal cancer